Primary entity: RAD-140Also known as: Testolone; RAD140; RAD 140Class: performance-adjacent literacy (see page)Cluster: Performance-adjacent
RAD-140 (Testolone) is an investigational selective androgen receptor modulator (SARM) developed historically for conditions such as muscle wasting and breast-cancer–related research contexts — not as an approved bodybuilding medicine. It is not a peptide, not FDA-approved for any indication, and is named among SARMs on the WADA Prohibited List (S1.2).
RAD-140 is not a peptide. It is a nonsteroidal SARM targeting the androgen receptor. Shop stacks that mix RAD-140 with peptides or “cardarine” are marketing clusters, not shared pharmacology.
Not FDA-approved. FDA has warned that SARMs are not legal dietary-supplement ingredients. WADA: RAD140 listed among example SARMs under S1.2 — prohibited at all times. Gray-market “RUO” bottles are not clinical trial supply.
Key takeaways
- Not a peptide — investigational SARM (Testolone).
- Not FDA-approved; not a lawful supplement active.
- WADA-prohibited (S1.2 example)
- SARM class carries documented hepatotoxicity case-report themes in recreational-use literature — literacy, not a protocol.
- No dosage / PCT charts on this site.
Questions this page answers
Next questions we answer on this page (curiosity / AI-gap map):
- What is RAD-140?
- Aliases
- Classification
- What it is NOT
- Mechanism
- Evidence ladder
- What has been studied
- Safety literacy
- Regulatory & WADA
- Why no dosages
- Related compounds
- Who for / not for
Who is this profile for — and who is it not for?
For: readers who need accurate SARM-vs-peptide and SARM-vs-steroid literacy for Testolone search demand.
Not for: anyone seeking buy links, bulk cycles, or PCT protocols.
What is RAD-140?
RAD-140 is a synthetic nonsteroidal SARM designed to agonize the androgen receptor with tissue-selective intent relative to classical anabolic-androgenic steroids. Development interest historically included muscle/bone and oncology-adjacent programs — none of which equals an approved consumer physique drug.
See also LGD-4033 and Ostarine for sibling SARM literacy.
| Chemistry class | Nonsteroidal SARM |
|---|---|
| Peptide? | No |
| Folk name | Testolone |
| U.S. approval | Not approved |
| Sport | WADA S1.2 |
Also known as
- RAD-140 / RAD140 / RAD 140 — research codes.
- Testolone
Online nickname— common folk/vendor name. - Mis-tags: “RAD peptide,” “Testolone peptide” — errors.
SARMs are AR ligands with a different medicinal-chemistry strategy than classical AAS; they are still anabolic agents under WADA and are not peptides.
How is RAD-140 classified?
Investigational SARM — unapproved drug substance. Not a dietary supplement. Performance-adjacent cluster for SERP demand next to peptides.
What is RAD-140 not?
| RAD-140 is not… | Why that matters |
|---|---|
| A peptide | Small-molecule SARM |
| FDA-approved | No U.S. approval |
| A dietary supplement ingredient | FDA has warned against SARMs in supplements |
| Something we dose or source | Refusal |
| Risk-free vs testosterone | Different profile ≠ no risk |
How is RAD-140 thought to work?
Selective androgen receptor modulation aiming for anabolic effects in muscle/bone with altered activity in other tissues versus testosterone/DHT — the core SARM design thesis. Mechanism thesis ≠ proven safe consumer use.
What human vs animal vs label evidence exists?
| Evidence type | What exists (summary) | Maturity |
|---|---|---|
| Human clinical | Limited clinical/developmental disclosures; no approved label | Human Incomplete |
| Animal / preclinical | Anabolic / AR pharmacology models | Animal |
| Recreational case reports | SARM-class liver-injury and other AE case series in literature | Human Safety signals (class) |
| Approved label | None | None |
This page does not invent lean-mass percentages.
What has RAD-140 been studied for?
Historical interest in muscle wasting, androgen biology, and oncology-adjacent AR programs. Recreational physique use is not an approved indication.
What safety topics come up?
No approved PI. SARM recreational-use literature includes hepatotoxicity case reports and hormonal-axis disruption themes. Product adulteration (wrong SARM, steroid contamination) is documented in supplement-testing literature. Not medical advice; not a monitoring protocol.
What is RAD-140's regulatory status?
- U.S.: Not FDA-approved. SARMs not legal as dietary-supplement ingredients
- WADA: RAD140 named under S1.2 SARMs
- Compounding: Not an approved compounded bodybuilding therapy in standard U.S. framing.
Why doesn't this page include a dosage chart?
Unapproved anabolic agent; “RAD-140 dosage / PCT” queries are protocol-seeking. Literacy refusal.
Related lab literacy
Not applicable to peptide reconstitution. What are peptides?.
Related compounds and comparisons
- LGD-4033 · Ostarine · YK-11 · S-23 · ACP-105
- MK-677 — often miscategorized as a SARM (it is not).
- Cardarine / SR9009 — non-SARM metabolic modulators often stacked in forums.
Frequently asked questions
Is RAD-140 a peptide?
No. It is a nonsteroidal SARM.
Is RAD-140 FDA approved?
No.
Is RAD-140 banned in sports?
Yes under WADA S1.2 SARMs framing.
Is Testolone the same as RAD-140?
Testolone is the common folk/vendor name for RAD-140.
Why no dosage / PCT chart?
YMYL refusal for unapproved anabolic self-experimentation.
Not a peptide, not FDA-approved, WADA-relevant, not medical advice. Disclaimer..
Sources
The sources below were checked against PubMed, DailyMed, or the official agency page on November 10, 2026 (America/Phoenix). Links go to the publisher, PubMed, or the agency record.
- Safety — human case Niazi B, Quach B, Fisher K, Peeraphatdit T. Cholestatic Drug-Induced Liver Injury From Rad-140 Successfully Treated With Corticosteroids. ACG Case Rep J. 2025. doi:10.14309/crj.0000000000001803. PMID: 40761329.
- Safety — human case Demangone MR, Abi Karam KR, Li J. Selective Androgen Receptor Modulators Leading to Liver Injury: A Case Report. Cureus. 2024. doi:10.7759/cureus.67958. PMID: 39328701.
- Safety Leciejewska N, Jędrejko K, Gómez-Renaud VM, et al. Selective androgen receptor modulator use and related adverse events including drug-induced liver injury: Analysis of suspected cases. Eur J Clin Pharmacol. 2024. doi:10.1007/s00228-023-03592-3. PMID: 38059982.
- Regulatory U.S. Food and Drug Administration. FDA Warns of Use of Selective Androgen Receptor Modulators (SARMs) Among Teens, Young Adults. Accessed November 10, 2026.
- Anti-doping World Anti-Doping Agency. The World Anti-Doping Code International Standard Prohibited List 2026. Accessed November 10, 2026. Confirm the current list and GlobalDRO before relying on sport status. The 2026 list names RAD140 as a SARM example under S1.2.
- Written by
- Peptide Tutorials Staff — a group of independent researchers & writers (not clinicians)
- Published · Updated
- Oct 7, 2026 · Oct 7, 2026 · Regulatory and sport-status wording checked November 10, 2026 against current FDA labels and the 2026 WADA Prohibited List · How we source & update
Educational disclaimer: Educational only. RAD-140 is not a peptide and is not FDA-approved. No dosing or buy links. We don't sell peptides. Read our full disclaimers.